Korean J Lab Med 2004; 24(5): 279-282  
Acute Panmyelosis with Myelofibrosis in Primary Myelodysplastic Syndrome
조용곤?김달식?이혜수?최삼임
Published online: October 1, 2004.
© Korean Society for Laboratory Medicine. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background :Acute panmyelosis with myelofibrosis categorized by WHO classification is a rare disease characterized by a rapid clinical course and hypercellular marrow with extensive myelofibrosis and proliferation of immature cells of trilineage. We describe a 73-year-old male with myelofibrosis and panmyelosis occuring in primary myelodysplastic syndrome (MDS). Six years ago, he had an operation for spinal lipomatosis, and three years later, the cause of his thrombocytopenia was diagnosed as MDS after a bone marrow examination. On admission, immature cells in the peripheral blood were increased and a bone marrow biopsy revealed myelofibrosis and a cluster of hypolobulated and/or nonlobulated megakaryocytes with 100% cellularity. Method : Result : Conclusion :
Keywords: Myelofibrosis, Myelodysplastic syndromes



This Article

e-submission

Archives

Indexed/Covered by