Ann Lab Med 2017; 37(2): 180-193  
Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines
Sollip Kim, M.D.1,*, Yeo-Min Yun, M.D.2,*, Hyo-Jin Chae, M.D.3, Hyun-Jung Cho, M.D.4, Misuk Ji, M.D.5, In-Suk Kim, M.D.6, Kyung-A Wee, M.D.7, Woochang Lee, M.D.8, Sang Hoon Song, M.D.9, Hye In Woo, M.D.10, Soo-Youn Lee, M.D.11, and Sail Chun, M.D.8
Department of Laboratory Medicine1, Ilsan Paik Hospital, Inje University College of Medicine, Goyang; Department of Laboratory Medicine2, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul; Department of Laboratory Medicine3, College of Medicine, The Catholic University of Korea, Seoul; Department of Laboratory Medicine4, Konyang University Hospital, College of Medicine, Konyang University, Daejeon; Department of Laboratory Medicine5, Veterans Health Service Medical Center, Seoul; Department of Laboratory Medicine6, School of Medicine, Pusan National University, Busan; Department of Laboratory Medicine7, Yonsei University College of Medicine, Seoul; Department of Laboratory Medicine8, University of Ulsan College of Medicine and Asan Medical Center, Seoul; Department of Laboratory Medicine9, Seoul National University Hospital and College of Medicine, Seoul; Department of Laboratory Medicine10, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon; Department of Laboratory Medicine and Genetics11, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Correspondence to: Soo-Youn Lee
Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea
Tel: +82-2-3410-1834 Fax: +82-2-3410-2719 E-mail: suddenbz@skku.edu
Co-corresponding author: Sail Chun
Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea
Tel: +82-2-3010-4513 Fax: +82-2-478-0884 E-mail: sailchun@amc.seoul.kr
* These authors contributed equally to this work.
Received: June 7, 2016; Revised: August 7, 2016; Accepted: December 11, 2016; Published online: March 1, 2017.
© The Korean Society for Laboratory Medicine. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Pharmacogenetic testing for clinical applications is steadily increasing. Correct and adequate use of pharmacogenetic tests is important to reduce unnecessary medical costs and adverse patient outcomes. This document contains recommended pharmacogenetic testing guidelines for clinical application, interpretation, and result reporting through a literature review and evidence-based expert opinions for the clinical pharmacogenetic testing covered by public medical insurance in Korea. This document aims to improve the utility of pharmacogenetic testing in routine clinical settings.
Keywords: Clinical laboratory, Korea, Pharmacogenetics, Testing, Practice guideline


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