Step 2. Prepare your manuscript

Article Type
Review (invited only)
Word count No limit
Abstract Up to 250 words (Structured/unstructured)
Tables/Figures No limit
References No limit
Original Article Word count Up to 3,500 words
Abstract Up to 250 words (Structured)
Tables/Figures Up to 6
References Up to 40
Brief Communication Word count Up to 1,500 words
Abstract Up to 200 words (Unstructured)
Tables/Figures Up to 3
References Up to 20
Opinion Word count Up to 1,500 words
Tables/Figures Up to 2
References Up to 15
Letter to the Editor Word count Up to 750 words
Tables/Figures Up to 2
References Up to 10

** Abstract and supplemental data were not permitted in case of Opinion and Letter to the Editor.


Use 12-point font size (Times New Roman)

Layout and spacing

  • Manuscript text should be double-spaced.
  • Do not format text in multiple columns.

Page and line numbers

Include page numbers and line numbers in the manuscript file.
Use continuous line numbers (do not restart the numbering on each page).


In the case of numbers greater than 3 digits, a comma should be inserted after every third digit from right to left (e.g., 5,431, 5,675, and 1,000), but a comma should not be inserted when indicating years (e.g., 1995, 2007).
Express percentages with one decimal place throughout the entire manuscript, unless using more than two decimal places is necessary.

Statistical significance

  • P should be uppercase and italicized to indicate statistical significance.
  • Report exact P-values for all values greater than or equal to 0.001.
    P-values less than 0.001 may be expressed as P< 0.001, or as exponentials in studies of genetic associations.


When using English abbreviations, define the abbreviation completely at first mention in the abstract, and original text. Do not use an abbreviation in the title. The terms listed at the end of the Ann Lab Med journal or its website need not be defined.

Reference style

  • Ann Lab Med uses “Vancouver” style, as outlined in the ICMJE sample references.
  • See reference formatting examples and additional instructions below.

Instrument or equipment

  • Mention the name of its model; manufacturer, city, (state), and country of an instrument or equipment in parentheses.
  • The general name of a reagent should be used.
  • If a trade name is expressed with a general name, it should be placed after it in parentheses.
  • When using a trade name, indicate the manufacturer, city, state, and country in parentheses.
  • Do not use the symbols TM or ® unless necessary.
  • At subsequent mentions after the first, instruments and equipments can be referred to indicating only the manufacturer in parentheses.

[Example] Coulter STKS (Coulter Electronics Inc., Hialeah, FL., USA), vancomycin (Sigma Chemical Company, St. Louis, MO, USA)

 Use correct and established nomenclature wherever possible.
 Use correct and established nomenclature wherever possible.
Units of measurement Use SI units.
Drugs Provide the Recommended International Non-Proprietary Name (rINN).
Species names Write in italics (e.g., Klebsiella pneumoniae). The name of a microorganism should be spelled out the first mention in the abstract, and original text. The names of the genus can be abbreviated subsequently (example: K. pneumoniae). However, do not abbreviate the name of the genus if 2 or more genera starting with the same letter are being referred to. Scientific names should always be italicized.
Gene symbols and variant nomenclature Human gene symbols are italicized capital letters (e.g., FBN1) and symbols for proteins are not italicized (e.g., fibrillin). Sequence variants should be described in the text and tables using both DNA and protein designations whenever appropriate. Sequence variant nomenclature must follow the current HGVS guidelines at, where examples of acceptable nomenclature are provided. Human gene nomenclature should follow the standards of the HUGO Gene Nomenclature Committee (HGNC), see
Allergens The systematic allergen nomenclature of the World Health Organization/International Union of Immunological Societies (WHO/IUIS) Allergen Nomenclature Sub-committee should be used for manuscripts that include the description or use of allergenic proteins. For manuscripts describing new allergens, the systematic name of the allergen should be approved by the WHO/IUIS Allergen Nomenclature Sub-Committee prior to manuscript publication. Examples of the systematic allergen nomenclature can be found at the WHO/IUIS Allergen Nomenclature site.
  • The title of the paper and a statement of its main point.
  • A statement that none of the material has been published or is under consideration elsewhere.
  • The Ann Lab Med will consider manuscripts that have been posted to a community preprint server; authors must disclose the preprint server and the accession number or DOI in their cover letter.
  • The corresponding author’s information (complete address, telephone number, and e-mail address)
  • Type of manuscript
  • The specific area
  • Title
  • Institutional affiliation(s), name and Open Researcher and Contributor ID (ORCID) of the author(s)
  • The corresponding author’s information (complete address, and e-mail address)
    1. If the authors are affiliated to different institutions, their names and affiliations should be stated the superscripts (1, 2, 3, etc) starting from the first author.
    2. Only the highest degree or title should be mentioned after the name, such as M.D., Ph.D., M.S., M.T., etc.
    3. A running title should be added if the title exceeds 50 characters in English, including spaces.
Download our sample title, author list, and affiliations page
 Use correct and established nomenclature wherever possible.
Original Article
  • 250 words limit
  • Subheadings: Background, Methods, Results, and Conclusions
  • Each subheading should be summarized in 1 paragraph.
Brief Communication
  • 200 words limit
  • Single paragraph without the subheadings
Letter to the Editor, Opinion Abstract is not permitted
  • In case of Review/Guideline, either structured or unstructured format is available.
  • Select 3 to 10 key words in English and insert them below the abstract
  • The key words are to be adjusted to the Medical Subject Heading (MeSH) of Index Medicus (
  • Following structure will be suitable:
    1. Introduction
    2. Materials and Methods (with subheadings, if any)
    3. Results (with subheadings, if any)
    4. Discussion (without subheadings)
  • Include a statement of ethical approval or statistical methods in the Materials and Methods section, if any.
  • Please abbreviate "Figure" as "Fig." when in the middle of a sentence.
Download our template file (word)
  • All potential conflicts of interests should be disclosed.
  • The following statement in its example format is required for Disclosure of conflict of interest.
    Include any additional information regarding the manuscript (i.e. sources of support, consulting fee or honorarium, support for travel to meetings for the study or other purposes, fee for participation in review activities such as data monitoring boards, payment for writing the manuscript, provision of writing assistance or equipment, board membership, patents, royalties, monetary interests in the products studied, consultantships, stocks, etc.) accordingly.
    1. Acknowledgments: General acknowledgements are described if applicable.
    2. Author contributions: Each author’s contribution(s) to the paper should be listed. We encourage you to follow the CRediT model (
    3. Conflict of interest: Declaration or None declared
    4. Research funding: Declaration or None declared

Ann Lab Med uses “Vancouver” style, as outlined in the ICMJE sample references.

 ICMJE sample references
Original Article
  • Mention the names of the authors, title, name of the journal, year published, volume number, and the first and last page numbers
  • List all the authors if the number of authors is less than 7, and list the first 6 authors followed by et al. if the number of authors is 7 or more.
  • If the manuscript has only 2 authors, use “and” and not a comma between their names.
  • Journal names are to be abbreviated in accordance with the style of Index Medicus (
  • In the case of a supplementary volume of a journal, record it in parentheses such as 75(S).
  • All the references in other languages should be translated into English.
Nieman LK, Biller BM, Findling JW, Newell-Price J, Savage MO, Stewart PM, et al. The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2008;93:1526-40.
Seo YJ, Oh I, Nam M, Shin S, Roh EY, Song EY. Comparison of four T-cell assays and two binding antibody assays in SARS-CoV-2 vaccinees with or without Omicron breakthrough infection. Ann Lab Med 2023;43:596-604.
Stanworth SJ and Shah A. How I use platelet transfusions. Blood 2022;140:1925-36.
  • Mention the name of the authors, editor(s), name of the book, edition, place published, publisher, publishing company, published year, and page number.
  • List it up to 2 authors.
Brecher ME, ed. Technical manual. 14th ed. Bethesda: American Association of Blood Banks, 2002: 485-96.
Alberts B, Bray D, et al. eds. Molecular biology of the cell. 3rd ed. New York: Garland Publishing, 1994: 491-9.
CLSI. User verification of precision and estimation of bias; approved guideline. 3rd ed. EP15-A3. Wayne, PA: Clinical and Laboratory Standards Institute, 2014.
Book chapter Indicate the name of author of the chapter, title of the chapter, ‘In:’, editors, name of the book, edition, place published, publishing company, published year, and page number.
Bylund DJ and Nakamura RM. Organ-specific autoimmune diseases. In: Henry JB, ed. Clinical diagnosis and management by laboratory methods. 20th ed. Philadelphia: WB Saunders, 2001:1000-15.
Website Author, website address, uniform resource locator (URL), and the date of recent update.
Mitelman F, Johansson B, and Mertens F (Eds.), Mitelman database of chromosome aberrations in cancer. (Updated on Nov 2023).
Deposited article(preprint) Kim J, Kim JW, Kim HY. Phenotypic and genotypic characterization of Listeria monocytogenes in clinical ruminant cases in Korea. bioRxiv [Preprint]. 2022.01.24.477645; doi:
  1. Cite tables in ascending numeric order upon first appearance in the manuscript file.
  2. Tables require a label (e.g., “Table 1”) and brief descriptive title to be placed above the table
    [Example] Table 1. Short title of the first table
  3. Vertical and horizontal lines should be omitted as much as possible.
  4. Text in the first column of a table should be aligned to the left. Single letters should be aligned centrally from the second column. If numbers are of the same unit, the decimal point should be the datum point. If there are symbols such as “-” indicating ranges, “±” and × symbols should be the datum point.
  5. Numbers with different units should be aligned to the right in all columns. If there are parentheses, the start of the parentheses and the last letter before it should be the datum point.
  6. Only numbers can be used without parentheses or a period if it represents a case in a table. A heading representing cases should be noted as “No. case” and a heading representing the number of cases should be noted as “N”.
  7. Explanations below should be in the order of superscripts and abbreviations. There should be a line break between the explanations of each superscript and/or abbreviations.
  8. The superscript should be placed on the right side of a word and should be used in the following order, “*, †, ‡, §, ||, ¶, **, ††, ‡‡, etc.”
  9. All nonstandard abbreviations should be explained below. Define them as indicated in the following examples. [Example] Abbreviations: NT, not tested and SAA, severe aplastic anemia
  1. Number the figures according to their order of citation in the text.
  2. The legends should be located below the figures.
    [Example] Fig. 1. Short title of the first figure.
  3. If a figure is a microphotograph, the staining methods and the magnification should be indicated.
  4. If a figure comprises 2 or more pictures, each should be explained either separately as “(A) explanation and (B) explanation” or together in parentheses.
  5. Minimum resolution required for a figure image is 300 dpi with figure file sizes of 80 mm in height and 80 mm in width.
  6. Acceptable file formats include BMP, JPG, PSD, TIF, AI, EMF, EPS, WMF, DOC, XLC, PPT and PDF.
  7. Expense of reproducing color photographs will be charged to the author(s). The author is responsible for submitting figure files that are of sufficient quality to permit accurate reproduction, and for approving the final color galley proof.
  1. Figures or tables too large for print, manuscript material that exceeds the limitation for the specific submission type, or appendices should be submitted for online publication only. These files should be marked and uploaded separately as supplemental files during submission and should be referenced within the text as supplemental data (i.e., “See Supplemental Data Table S1”, “See Supplemental Data Fig. S1”, etc.).
  2. Please assess the necessity of the material before submission, as only essential materials are allowed to be presented as supplemental data.
  3. It’s vital that you carefully check your supplemental files before submission as any modification after your paper is published will require a formal correction.
  4. We do not edit, typeset or proof supplemental files , so please present it clearly and succinctly at initial submission, making sure it conforms to the style and terminology of the rest of the paper.
  5. Keep file sizes as small as possible, with a maximum size of 50 MB, so that they can be downloaded quickly.
Annals of Laboratory Medicine
Journal Information July, 2024
Vol.44 No.4
Latest Issue All Issues

Cover Image


Search for

Editorial Office

Fax +82-2-790-4760