Clinical utility of M2BPGi in chronic liver diseases. The M2BPGi levels increase as the disease progresses from minimal liver fibrosis to decompensated cirrhosis. M2BPGi can be used to assess disease status, such as liver fibrosis, HCC risk, HCC recurrence risk, liver function, and prognosis of chronic liver diseases, with the progression of the disease.

Abbreviations: M2BPGi, Mac-2 binding protein glycosylation isomer; HCC, hepatocellular carcinoma.