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Table. 2. Table 2

Comparison of Ct values in paired upper and lower respiratory tract samples obtained from newly diagnosed COVID-19 patients (N =1,916)

SARS-CoV-2 target gene	NPS vs. sputum (N=909)				NPS/OPS vs. sputum (N=1,007)

	Ct value, Median (IQR)		Ct difference, Median (IQR)		Ct value, Median (IQR)		Ct difference, Median (IQR)

	NPS	Sputum	Sputum-NPS	P^{^{^*}}	NPS/OPS	Sputum	Sputum-NPS	P^{^{^*}}
E	24.61 (19.20-29.51)	24.57 (19.57-29.06)	0.22 (-0.16-0.59)	>0.05	24.69 (18.59-29.65)	24.82 (19.24-29.52)	0.19 (-0.14-0.51)	>0.05
RdRp	25.65 (20.33-30.42)	25.82 (20.95-30.12)	0.28 (-0.07-0.64)	>0.05	25.66 (19.97-30.86)	25.89 (20.49-30.72)	0.29 (-0.03-0.61)	>0.05
N	26.97 (21.58-31.29)	27.12 (22.31-31.34)	0.49 (0.11-0.88)	0.034	26.89 (21.22-31.79)	27.18 (21.97-31.95)	0.43 (0.07-0.80)	>0.05

^*Bonferroni-corrected P.

Abbreviations: COVID-19, coronavirus disease 2019; Ct, threshold cycle; E, envelope; IQR, interquartile range; N, nucleocapsid; NPS, nasopharyngeal swab; OPS, oropharyngeal swab; RdRp, RNA-dependent RNA polymerase; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Ann Lab Med 2021;41:225~229 https://doi.org/10.3343/alm.2021.41.2.225