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Table. 4.

Table. 4.

Calibrator reconstitution and storage experiment results

Experiment Drug Condition Coefficient β2 (95% CI) P* Expected concentration at 6 ng/mL (%diff)
Reconstitution TAC A0 Baseline 6.000 (Baseline)
B0 0.00012 (-0.00034–0.00058) 0.612 5.997 (-0.049)
SIR A0 Baseline 6.000 (Baseline)
B0 -0.00005 (-0.00043–0.00032) 0.772 6.002 (0.029)
EVE A0 Baseline 6.000 (Baseline)
B0 -0.00015 (-0.00036–0.00005) 0.141 6.007 (0.112)
Storage TAC A1 Baseline 6.000 (Baseline)
A2 -0.00037 (-0.00102–0.00028) 0.257 6.009 (0.143)
A3 -0.00028 (-0.00093–0.00037) 0.386 6.007 (0.109)
A4 -0.00022 (-0.00087–0.00043) 0.496 6.005 (0.086)
SIR A1 Baseline 6.000 (Baseline)
A2 -0.00157 (-0.00239–-0.00076) < 0.001 6.033 (0.555)
A3 -0.00091 (-0.00173–-0.00009) 0.030 6.019 (0.321)
A4 -0.00061 (-0.00143–0.00020) 0.138 6.013 (0.217)
EVE A1 Baseline 6.000 (Baseline)
A2 -0.00043 (-0.00098–0.00012) 0.121 6.013 (0.222)
A3 -0.00117 (-0.00172–-0.00062) < 0.001 6.036 (0.598)
A4 -0.00075 (-0.00130–-0.00020) 0.009 6.023 (0.384)

*P from t-test on coefficient β2.

Abbreviations: CI, confidence interval; EVE, everolimus; TAC, tacrolimus; SIR, sirolimus.

Ann Lab Med 2021;41:268~276 https://doi.org/10.3343/alm.2021.41.3.268

© Ann Lab Med