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Table. 1.

Table. 1.

Demographic features and laboratory findings in patients with KD and patients with other acute febrile illnesses at the time of diagnosis

Patients with KD Patients with other acute febrile illnesses P


N Value N Value
Age (yr), median (range) 77 1.9 (0.03–6.9) 32 2.1 (0.1–8.1) 0.670
Sex (male/female) 77 50/27 32 23/9 0.513
Total duration of fever (days), median (range) 77 6 (1–14) 32 6 (1–14) 0.337
Duration of fever before admission (days), median (range) 77 4 (1–13) 32 4 (1–8) 0.668
WBCs (× 109/L), (mean ± SD) 76 14.5 ± 4.6 32 11.9 ± 5.8 0.014
Neutrophils (Proportion of 1.0), median (range) 76 0.66 (0.26–0.95) 32 0.66 (0.21–0.86) 0.336
Eosinophils (Proportion of 1.0), median (range) 76 0.02 (0.00–0.14) 32 0.01 (0.00–0.06) < 0.001
Hemoglobin (g/L), (mean ± SD) 76 111 ± 12 32 116 ± 13 0.099
Platelets (× 109/L), median (range) 76 349 (132–888) 32 259 (162–510) < 0.001
Erythrocyte sedimentation rate (mm/hr), (mean ± SD) 48 74 ± 27 10 30 ± 20 < 0.001
CRP (mg/L), median (range) 77 84 (8–232) 32 45 (5–118) < 0.001
AST (µkat/L), median (range) 74 0.53 (0.27–7.10) 32 0.58 (0.32–1.79) 0.373
ALT (µkat/L), median (range) 74 0.61 (0.08–9.32) 32 0.28 (0.13–2.57) 0.003
Total bilirubin (µmol/L), median (range) 36 12.0 (3.4–68.4) 9 10.6 (5.1–65.0) 0.425
Total protein (g/L), (mean ± SD) 70 65±7 30 66±5 0.217
Albumin (g/L), median (range) 72 37 (26–45) 31 40 (20–44) 0.050
Sodium (mmol/L), median (range) 73 136 (127–141) 31 137 (130–143) 0.064
Potassium (mmol/L), (mean ± SD) 73 4.4 ± 0.5 31 4.2 ± 0.5 0.075
Chloride (mmol/L), (mean ± SD) 73 101.0 ± 12.3 31 103.9 ± 3.2 0.017
Creatine kinase (µkat/L), median (range) 50 0.8 (0.2–11.2) 19 1.4 (0.7–4.2) 0.053
Creatine kinase-MB (µg/L), median (range) 64 14.2 (2.2–35.9) 28 15.0 (4.0–33.6) 0.391
NT-proBNP (ng/L), median (range) 75 788 (56–3,500) 20 204 (21–2,069) < 0.001
Ferritin (µg/L), median (range) 77 188.8 (25.5–750.5) 32 106.8 (11.1–632.2) 0.003

The statistical significance of differences between males and females was assessed by the Chi-square test. White blood cell count, hemoglobin, ESR, total protein, potassium, and chloride were analyzed using Student’s t-test. Results of the other laboratory tests were analyzed using the Mann–Whitney U-test.

Abbreviations: KD, Kawasaki disease; WBC, white blood cell count; CRP, C-reactive protein; AST, aspartate aminotransferase; ALT, alanine aminotransferase; creatine kinase-MB, cardiac isoenzyme of creatine kinase; NT-proBNP, N-terminal pro-brain natriuretic peptide; SD, standard deviation.

Ann Lab Med 2021;41:318~322 https://doi.org/10.3343/alm.2021.41.3.318

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