Preoperative and intraoperative patient characteristics
Variable | No MAKE (N = 91) | MAKE (N = 9) | No AKI (N = 91) | AKI (N = 9) | ||
---|---|---|---|---|---|---|
Age (yr) | 0.078 | 0.078 | ||||
25–50 | 12 (13.2) | 0 (0) | 12 (13.2) | 0 (0) | ||
51–70 | 43 (47.3) | 2 (22.2) | 43 (47.3) | 2 (22.2) | ||
71–90 | 36 (39.6) | 7 (77.8) | 36 (39.6) | 7 (77.8) | ||
Preoperative eGFR < 60 mL/min (CKD-EPI), |
23 (25.3) | 6 (66.6) | 0.009 | 24 (26.4) | 5 (55.6) | 0.116 |
Left ventricular ejection fraction, % | 50 (40–60) | 55 (25–60) | 0.609 | 50 (40–60) | 55 (25–60) | 0.739 |
Pulmonary hypertension, |
26 (28.6) | 3 (3.3) | 0.716 | 26 (28.6) | 3 (3.3) | 0.716 |
Atrial fibrillation, |
25 (27.5) | 3 (33.3) | 0.024 | 25 (27.5) | 6 (66.6) | 0.024 |
Peripheral vascular disease, |
19 (20.9) | 2 (22.2) | > 0.99 | 17 (18.9) | 4 (44.4) | 0.089 |
Diabetes mellitus on medication, |
17 (18.9) | 3 (3.3) | 0.378 | 17 (18.9) | 3 (3.3) | 0.378 |
Hypercholesterolemia, |
58 (63.7) | 6 (66.6) | > 0.99 | 58 (63.7) | 6 (66.6) | > 0.99 |
Preoperative medication | ||||||
Renin-angiotensin-aldosterone system inhibitors, |
47 (51.7) | 7 (77.8) | 0.134 | 46 (50.5) | 8 (88.9) | 0.036 |
β-blockers, |
64 (70.3) | 8 (88.9) | 0.237 | 63 (69.2) | 9 (100) | 0.050 |
Calcium channel blockers, |
30 (33.0) | 4 (44.4) | 0.485 | 30 (33.0) | 4 (44.4) | 0.485 |
Diuretics, |
52 (57.1) | 7 (77.8) | 0.230 | 52 (57.1) | 7 (77.8) | 0.230 |
Statins, |
48 (52.8) | 5 (55.6) | > 0.99 | 48 (52.8) | 5 (55.6) | > 0.99 |
Cross-clamp time, min | 72 (56–89) | 96 (65–153) | 0.055 | 73 (56–89) | 66 (59–153) | 0.350 |
Numbers denote median (25th–75th percentile) or N (%) as appropriate.
*
Abbreviations: AKI, acute kidney injury; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration equation for estimation of glomerular filtration rate; eGFR, estimated glomerular filtration rate; MAKE, major adverse kidney events.
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