Table. 1. Table 1

Informative SNVs and variant allele frequency distributions of 39 recipients according to days post-transplantation

Recipient number	N informative SNVs*	Outcome	Days after transplantation	% VAF of informative SNVs	Mean depth
KT01	11	Non-AR	28	0.315	8,156
			105	0.262	13,898
			168	1.476	10,231
KT02	7	Non-AR	168	0.885	11,317
			196	6.545	9,866
KT03	11	AR	14	2.008	7,338
			21	15.189	234
			35	1.798	12,158
KT04	10	Non-AR	28	7.863	3,872
			56	14.164	1,481
			112	19.335	290
			168	28.726	953
			196	60.878	798
KT05	10	AR	14	18.449	687
			28	60.199	859
			98	41.693	1,059
KT06	6	Non-AR	21	0.15	1,170
			84	0.22	1,181
			224	27.358	379
KT07	16	AR	7	10.279	6,257
			28	14.012	3,574
			56	16.531	2,002
			84	6.016	10,501
KT08	13	AR	14	71.87	215
			49	74.835	7,369
			140	74.182	6,140
			168	87.5	667
KT09	12	Non-AR	7	22.247	200
			14	3.045	9,065
KT10	6	Non-AR	14	12.29	253
			28	3.69	5,120
			168	60.259	953
			196	50.038	2,836
KT11	7	Non-AR	56	15.27	198
			168	53.733	197
			196	66.709	570
KT12	13	Non-AR	21	0.747	16,881
			63	1.112	21,639
			112	0.541	17,665
			196	1.772	7,821
KT13	3	Non-AR	21	7.485	2,917
			98	1.096	12,332
			140	6.866	6,218
KT14	15	Non-AR	7	6.55	7,994
			35	60.226	184
			84	18.166	1,129
			196	71.989	299
KT15	4	Non-AR	7	9.766	1,083
			14	1.482	3,149
			21	1.729	9,980
			28	1.589	16,213
			84	1.274	10,194
			112	4.617	5,072
			168	3.48	10,687
			196	3.642	9,194
KT16	5	AR	7	47.212	4,863
			14	30.175	11,197
			28	38.849	326
KT17	6	Non-AR	7	14.444	1,131
			14	0.877	10,340
			21	1.427	8,684
			28	0.545	9,756
			56	0.279	8,548
KT18	14	Non-AR	14	14.217	1,374
			21	7.008	2,124
			56	6.775	986
			168	10.675	544
KT19	10	Non-AR	21	7.199	6,390
			28	15.113	2,201
			56	21.449	9,504
			140	30.468	1,179
			168	24.242	690
KT20	6	Non-AR	14	5.373	7,910
			28	2.724	6,112
			56	10.671	4,680
			84	7.544	1,307
KT21	11	Non-AR	14	1.104	6,741
			21	0.773	6,372
			28	1.302	6,693
			56	2.892	3,462
			112	1.416	1,820
			140	2.39	1,972
			168	2.231	1,138
KT22	10	AR	7	37.995	595
			28	2.386	7,236
			35	5.667	1,772
KT23	7	Non-AR	21	57.325	443
			28	9.601	694
			56	44.057	3,159
			140	12.425	1,103
			168	26.747	164
KT24	12	Non-AR	7	0.779	7,900
			14	20.215	212
KT25	6	Non-AR	21	31.853	1,733
			28	76.37	1,202
			56	39.785	529
			98	11.965	1,084
			140	34.996	155
			168	67.116	358
KT26	14	Non-AR	7	4.451	2,753
			21	3.166	6,206
			28	1.564	577
			56	7.804	5,964
			168	6.526	3,915
			196	27.5	117
KT27	13	Non-AR	21	75.125	4,275
			28	70.905	861
			56	47.568	179
			84	69.772	575
			112	62.085	319
			140	55.039	1,018
KT28	18	Non-AR	7	73.252	4,460
			21	51.656	298
			28	71.759	2,175
			49	68.115	2,853
			84	69.13	2,829
			112	70.321	1,243
			140	64.442	6,659
KT29	16	Non-AR	7	81.141	1,448
			14	87.269	156
KT30	19	Non-AR	7	59.978	215
			21	83.587	607
KT31	10	Non-AR	7	3.449	15,343
			14	3.683	2,645
KT32	12	Non-AR	7	1.42	4,315
			14	9.069	314
KT33	11	AR	7	22.03	7,999
			21	5.062	19,788
			56	4.564	20,496
KT34	7	Non-AR	14	9.213	293
			21	6.532	13,266
			28	9.941	2,271
			56	10.483	5,422
KT35	9	Non-AR	14	10.816	517
			28	11.187	2,630
			56	23.901	177
			84	17.485	271
KT36	14	Non-AR	14	27.191	814
			28	14.659	1,620
			56	18.461	201
KT37	13	AR	14	14.544	2,919
			21	14.918	3,103
			56	28.527	1,219
			63	22.442	2,787
KT38	10	Non-AR	7	45.796	156
			28	14.405	159
KT39	10	AR	14	2.542	7,328
			28	49.321	402
			35	4.727	499

*The following 39 SNV markers were used for the chimerism calculation: rs3738561, rs6480497, rs4757113, rs7983800, rs3745331, rs10426644, rs2540307, rs1358833, rs62270249, rs1436501, rs9386037, rs2159478, rs11023112, rs6589967, rs8022985, rs1202017, rs645107, rs6921313, rs4072990, rs6676162, rs72735619, rs11187560, rs10832201, rs7950719, rs6590643, rs1731550, rs10777988, rs4496026, rs12327492, rs1348784, rs281544, rs6445350, rs3819864, rs6863833, rs1423013, rs1561681, rs73230060, rs6995506, and rs16904057.

Abbreviations: SNV, single-nucleotide variant; VAF, variant allele frequency; AR, acute rejection, including acute antibody-mediated rejection and T cell-mediated rejection.

Ann Lab Med 2021;41:469~478 https://doi.org/10.3343/alm.2021.41.5.469