pISSN 2234-3806eISSN 2234-3814
Table. 1.
Clinical characteristics of patients with GH and NGH in the derivation and validation cohorts
| Derivation cohort | Validation cohort | |||||
|---|---|---|---|---|---|---|
| GH | NGH | GH | NGH | |||
| Number of patients | 101 | 55 | 47 | 60 | 0.001 | |
| Male, N (%) | 44 (43.6) | 31 (56.4) | 0.126 | 25 (53.2) | 37 (61.7) | 0.380 |
| Age (yr), median (IQR) | 51 (36–64) | 65 (49–72) | 0.001 | 55 (20–91) | 60.5 (6–85) | 0.945 |
| RBC count (/μL), median (IQR) | 65.1 (29.7–122.2) | 89.8 (39.0–914.1) | 0.003 | 73.1 (33.0–219.9) | 102.65 (39.8–781.1) | 0.215 |
| Dysmorphic RBC (%), N (%) |
<0.001 | 0.143 | ||||
| 0% | 30 (38.5) | 17 (73.9) | 11 | 10 | ||
| 1%–10% | 37 (47.4) | 5 (21.7) | 15 | 5 | ||
| 11%–20% | 7 (9.0) | 1 (4.3) | 0 | 1 | ||
| 21%–30% | 2 (2.6) | 0 | 0 | 0 | ||
| >31%–40% | 2 (2.6) | 0 | 0 | 0 | ||
| Urinary protein concentration (mg/L), median (IQR) |
471 (228–1,200) | 150 (102–813) | 0.017 | 510 (111–15.5) | 207 (79–468) | 0.061 |
| Urinary dipstick scores of protein, N (%) |
0.003 | <0.001 | ||||
| Negative | 24 (23.8) | 28 (50.9) | 14 (29.8) | 37 (61.7) | ||
| Trace | 17 (16.8) | 1 (1.8) | 4 (8.5) | 7 (11.7) | ||
| 1+ | 28 (27.7) | 15 (27.3) | 9 (19.1) | 13 (21.7) | ||
| 2+ | 7 (6.9) | 4 (7.3) | 8 (17.0) | 0 | ||
| 3+ | 9 (8.9) | 4 (7.3) | 12 (25.5) | 2 (3.3) | ||
| 4+ | 16 (15.8) | 3 (5.5) | 0 | 1 (1.7) | ||
*101 and 42 of samples had accompanying dysmorphic RBC(%) results in the derivation and validation cohorts, respectively; †113 and 76 of samples had accompanying urinary protein concentration results in the derivation and validation cohorts, respectively; ‡156 and 107 of samples had accompanying urinary dipstick scores of protein results in the derivation and validation cohorts, respectively.
Abbreviations: GH, glomerular hematuria; NGH, non-glomerular hematuria; IQR, interquartile range; RBC, red blood cell.
Ann Lab Med 2022;42:160~168 https://doi.org/10.3343/alm.2022.42.2.160
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