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Table. 1.

Table. 1.

Clinical characteristics of patients with GH and NGH in the derivation and validation cohorts

Derivation cohort Validation cohort
GH NGH P GH NGH P
Number of patients 101 55 47 60 0.001
Male, N (%) 44 (43.6) 31 (56.4) 0.126 25 (53.2) 37 (61.7) 0.380
Age (yr), median (IQR) 51 (36–64) 65 (49–72) 0.001 55 (20–91) 60.5 (6–85) 0.945
RBC count (/μL), median (IQR) 65.1 (29.7–122.2) 89.8 (39.0–914.1) 0.003 73.1 (33.0–219.9) 102.65 (39.8–781.1) 0.215
Dysmorphic RBC (%), N (%)* <0.001 0.143
0% 30 (38.5) 17 (73.9) 11 10
1%–10% 37 (47.4) 5 (21.7) 15 5
11%–20% 7 (9.0) 1 (4.3) 0 1
21%–30% 2 (2.6) 0 0 0
>31%–40% 2 (2.6) 0 0 0
Urinary protein concentration (mg/L), median (IQR) 471 (228–1,200) 150 (102–813) 0.017 510 (111–15.5) 207 (79–468) 0.061
Urinary dipstick scores of protein, N (%) 0.003 <0.001
Negative 24 (23.8) 28 (50.9) 14 (29.8) 37 (61.7)
Trace 17 (16.8) 1 (1.8) 4 (8.5) 7 (11.7)
1+ 28 (27.7) 15 (27.3) 9 (19.1) 13 (21.7)
2+ 7 (6.9) 4 (7.3) 8 (17.0) 0
3+ 9 (8.9) 4 (7.3) 12 (25.5) 2 (3.3)
4+ 16 (15.8) 3 (5.5) 0 1 (1.7)

*101 and 42 of samples had accompanying dysmorphic RBC(%) results in the derivation and validation cohorts, respectively; 113 and 76 of samples had accompanying urinary protein concentration results in the derivation and validation cohorts, respectively; 156 and 107 of samples had accompanying urinary dipstick scores of protein results in the derivation and validation cohorts, respectively.

Abbreviations: GH, glomerular hematuria; NGH, non-glomerular hematuria; IQR, interquartile range; RBC, red blood cell.

Ann Lab Med 2022;42:160~168 https://doi.org/10.3343/alm.2022.42.2.160

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