Distribution of UF-5000 parameters in GH and NGH patients in the derivation and validation cohorts
Parameter | Derivation cohort | Validation cohort | ||||
---|---|---|---|---|---|---|
GH Median value (IQR) |
NGH Median value (IQR) |
GH Median value (IQR) |
NGH Median value (IQR) |
|||
URD (%) | 61.2 (44.1–84.1) | 20.1 (1.9–52.1) | <0.001 | 49.5 (38.9–64.6) | 9.6 (2.7–38.0) | <0.001 |
Small RBC (%) | 55.9 (42.6–68.4) | 19.6 (1.9–49.0) | <0.001 | 46.7 (38.5–63.3) | 9.5 (2.7–36.3) | <0.001 |
Lysed RBC (%) | 3.8 (1.2–8.6) | 1.0 (0.2–3.7) | <0.001 | 2.2 (0.6–7.8) | 1.0 (0.1–3.1) | 0.010 |
RBC-P70FSC (ch) | 100 (76.8–111.5) | 145 (107.0–163.0) | <0.001 | 110 (93.0–130.0) | 154 (115.0–165.5) | <0.001 |
RBC-SF-FSC-W (ch) | 48 (40.0–60.0) | 36 (24.0–61.5) | 0.009 | 50 (42.0–66.0) | 35 (24.0–45.5) | <0.001 |
Mean FSC |
83 (65.5–95.0) | 120 (90.3–148) | <0.001 | - | - | - |
Mean SSC |
79.5 (57.5–105.5) | 81 (60.5–97.2) | 0.897 | - | - | - |
*Mean FSC and SSC values were not obtained in the validation cohort.
Abbreviations: GH, glomerular hematuria; NGH, non-glomerular hematuria; IQR, interquartile range; URD, urinary RBC distribution; RBC, red blood cell; SF, surface channel; FSC, forward-scattered light; SSC, side-scattered light; ch, channel; W, width.
© Ann Lab Med