Table. 2. Table 2

Antimicrobial susceptibility of the 76 Fusobacterium isolates tested in this study

Organism and antimicrobial agent	MIC (μg/mL)			Susceptibility (%)
Organism and antimicrobial agent	Range	50%	90%	S	I	R
Fusobacterium nucleatum (N=17)
Penicillin G	≤0.12–0.25	≤0.12	0.25	100	0	0
Piperacillin-tazobactam	≤0.12	≤0.12	≤0.12	100	0	0
Cefoxitin	≤0.12–1	0.25	1	100	0	0
Cefotetan	≤0.12–0.25	≤0.12	0.25	100	0	0
Ceftriaxone	≤0.12–0.5	≤0.12	0.5	100	0	0
Imipenem	≤0.12	≤0.12	≤0.12	100	0	0
Clindamycin	≤0.12	≤0.12	≤0.12	100	0	0
Moxifloxacin	≤0.12–0.25	≤0.12	0.25	100	0	0
Chloramphenicol	0.5–1	1	1	100	0	0
Metronidazole	≤0.12–0.5	≤0.12	0.5	100	0	0
Fusobacterium necrophorum (N=21)
Penicillin G	≤0.12	≤0.12	≤0.12	100	0	0
Piperacillin-tazobactam	≤0.12–0.25	≤0.12	≤0.12	100	0	0
Cefoxitin	≤0.12–1	≤0.12	1	100	0	0
Cefotetan	≤0.12–2	≤0.12	2	100	0	0
Ceftriaxone	≤0.12–0.5	≤0.12	0.25	100	0	0
Imipenem	≤0.12–1	≤0.12	≤0.12	100	0	0
Clindamycin	≤0.12	≤0.12	≤0.12	100	0	0
Moxifloxacin	0.5–2	1	2	100	0	0
Chloramphenicol	0.25–2	1	2	100	0	0
Metronidazole	≤0.12–1	≤0.12	0.5	100	0	0
Fusobacterium varium (N=25)
Penicillin G	≤0.12–1	0.25	0.5	96	4	0
Piperacillin-tazobactam	1–16	4	8	100	0	0
Cefoxitin	2–16	4	16	100	0	0
Cefotetan	≤0.12–64	2	16	92	0	8
Ceftriaxone	1−>128	4	8	96	0	4
Imipenem	0.5–2	1	2	100	0	0
Clindamycin	1−>128	4	32	36	16	48
Moxifloxacin	2–32	4	16	24	52	24
Chloramphenicol	2–4	4	4	100	0	0
Metronidazole	≤0.12–1	0.5	0.5	100	0	0
Fusobacterium mortiferum (N=9)*
Penicillin G	≤0.12–2	1	2	44	33	22
Piperacillin-tazobactam	0.25–8	2	8	100	0	0
Cefoxitin	2–8	4	4	100	0	0
Cefotetan	1–4	2	4	100	0	0
Ceftriaxone	8−>128	64	128	11	22	67
Imipenem	0.5–1	1	1	100	0	0
Clindamycin	≤0.12–0.5	≤0.12	0.5	100	0	0
Moxifloxacin	0.5–2	0.5	0.5	89	0	11
Chloramphenicol	0.5–1	0.5	1	100	0	0
Metronidazole	0.25–1	0.25	0.5	100	0	0
Fusobacterium spp. (N=4)†
Penicillin G	≤0.12	≤0.12	≤0.12	100	0	0
Piperacillin-tazobactam	≤0.12–1	≤0.12	1	100	0	0
Cefoxitin	≤0.12–0.5	≤0.12	0.5	100	0	0
Cefotetan	≤0.12–0.25	≤0.12	0.25	100	0	0
Ceftriaxone	≤0.12	≤0.12	≤0.12	100	0	0
Imipenem	≤0.12	≤0.12	≤0.12	100	0	0
Clindamycin	≤0.12–1	≤0.12	1	100	0	0
Moxifloxacin	≤0.12–16	2	16	75	0	25
Chloramphenicol	0.5–2	0.5	2	100	0	0
Metronidazole	≤0.12–0.5	≤0.12	0.5	100	0	0

*F. mortiferum, isolated from blood (N=3), abdomen (N=5), and foot wound (N=1); ^†Fusobacterium spp., including F. canifelinum (N=1) isolated from perianal abscess aspirate, F. periodonticum (N=2) isolated from blood, and F. ulcerans (N=1) isolated from abdomen.

Abbreviations: MIC, minimum inhibitory concentration; S, susceptible; I, intermediate; R, resistant.

Ann Lab Med 2022;42:188~195 https://doi.org/10.3343/alm.2022.42.2.188