pISSN 2234-3806eISSN 2234-3814
Basic patient characteristics
| Parameter | Total (N=152) |
|---|---|
| Age (yr) | 50.2±10.9 |
| Sex | |
| Male (N, %) | 97 (63.8) |
| Female (N, %) | 55 (36.2) |
| LC (N, %) | 46 (30.3) |
| TE (kPa) | 4.7 (3.9–6.5) |
| F0/1 (no or minimal) (≤7.0 kPa) (N, %) | 117 (77.0) |
| F2 (moderate) (≥7.1 kPa) (N, %) | 19 (12.5) |
| F3 (severe) (≥10.0 kPa) (N, %) | 7 (4.6) |
| F4 (cirrhosis) (≥13.0 kPa) (N, %) | 9 (5.9) |
| AST (U/L) | 28.0 (23.0–34.0) |
| ALT (U/L) | 26.0 (19.0–41.8) |
| ALP (U/L) | 63.5 (52.0–75.0) |
| GGT (U/L) |
37.0 (22.0–67.5) |
| PLT (×109/L) |
191.0 (165.0–234.0) |
| PT (sec/%/INR) |
13.2 (12.7–13.7)/99.0 (92.0–107.5)/1.0 (0.9–1.1) |
| aPTT (sec) |
34.8 (32.2–37.2) |
| AST/ALT | 1.1 (0.8–1.4) |
| APRI |
0.3 (0.2–0.5) |
| FIB-4 |
1.4 (1.0–2.1) |
| ELF | 8.9 (8.2–9.6) |
| None/mild (<7.7) (N, %) | 2 (1.3) |
| Moderate (7.7–9.8) (N, %) | 124 (81.6) |
| Severe (≥9.8) (N, %) | 26 (17.1) |
| M2BPGi (COI) | 0.5 (0.3–0.7) |
| - (<1.0) (N, %) | 134 (88.2) |
| 1+ (1.0–3.0) (N, %) | 13 (8.6) |
| 2+ (≥3.0) (N, %) | 5 (3.3) |
| HBV DNA (copies/mL) |
120.0 (0.0–436.8) |
Data are presented as mean±SD, median (interquartile range), or number (percentage). Data of APRI, FIB-4, ELF, and M2BPGi according to the fibrosis grade based on TE are summarized in Supplemental Data Table S1.
*GGT levels were obtained from 71 patients at enrollment. †PLT levels and APRI and FIB-4 scores were obtained from 130 CHB patients at enrollment. ‡PT levels were obtained from 112 CHB patients at enrollment. §aPTT levels were obtained from 11 CHB patients at enrollment. ||HBV DNA levels were obtained from 137 CHB patients at enrollment.
Abbreviations: LC, liver cirrhosis; TE, transient elastography; kPa, kilopascal; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyltransferase; PLT, platelet count; PT, prothrombin time; INR, international normalized ratio; aPTT, activated partial thromboplastin time; APRI, AST-to-platelet ratio index; FIB-4, fibrosis-4; ELF, enhanced liver fibrosis; M2BPGi, Mac-2 binding protein glycosylation isomer; COI, cut-off index; HBV, hepatitis B virus; DNA, deoxyribonucleic acid; SD, standard deviation.
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