OPEN ACCESS pISSN 2234-3806
eISSN 2234-3814

Table. 1.

Table. 1.

Basic patient characteristics

Parameter Total (N=152)
Age (yr) 50.2±10.9
Sex
Male (N, %) 97 (63.8)
Female (N, %) 55 (36.2)
LC (N, %) 46 (30.3)
TE (kPa) 4.7 (3.9–6.5)
F0/1 (no or minimal) (≤7.0 kPa) (N, %) 117 (77.0)
F2 (moderate) (≥7.1 kPa) (N, %) 19 (12.5)
F3 (severe) (≥10.0 kPa) (N, %) 7 (4.6)
F4 (cirrhosis) (≥13.0 kPa) (N, %) 9 (5.9)
AST (U/L) 28.0 (23.0–34.0)
ALT (U/L) 26.0 (19.0–41.8)
ALP (U/L) 63.5 (52.0–75.0)
GGT (U/L)* 37.0 (22.0–67.5)
PLT (×109/L) 191.0 (165.0–234.0)
PT (sec/%/INR) 13.2 (12.7–13.7)/99.0 (92.0–107.5)/1.0 (0.9–1.1)
aPTT (sec)§ 34.8 (32.2–37.2)
AST/ALT 1.1 (0.8–1.4)
APRI 0.3 (0.2–0.5)
FIB-4 1.4 (1.0–2.1)
ELF 8.9 (8.2–9.6)
None/mild (<7.7) (N, %) 2 (1.3)
Moderate (7.7–9.8) (N, %) 124 (81.6)
Severe (≥9.8) (N, %) 26 (17.1)
M2BPGi (COI) 0.5 (0.3–0.7)
- (<1.0) (N, %) 134 (88.2)
1+ (1.0–3.0) (N, %) 13 (8.6)
2+ (≥3.0) (N, %) 5 (3.3)
HBV DNA (copies/mL)|| 120.0 (0.0–436.8)

Data are presented as mean±SD, median (interquartile range), or number (percentage). Data of APRI, FIB-4, ELF, and M2BPGi according to the fibrosis grade based on TE are summarized in Supplemental Data Table S1.

*GGT levels were obtained from 71 patients at enrollment. PLT levels and APRI and FIB-4 scores were obtained from 130 CHB patients at enrollment. PT levels were obtained from 112 CHB patients at enrollment. §aPTT levels were obtained from 11 CHB patients at enrollment. ||HBV DNA levels were obtained from 137 CHB patients at enrollment.

Abbreviations: LC, liver cirrhosis; TE, transient elastography; kPa, kilopascal; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyltransferase; PLT, platelet count; PT, prothrombin time; INR, international normalized ratio; aPTT, activated partial thromboplastin time; APRI, AST-to-platelet ratio index; FIB-4, fibrosis-4; ELF, enhanced liver fibrosis; M2BPGi, Mac-2 binding protein glycosylation isomer; COI, cut-off index; HBV, hepatitis B virus; DNA, deoxyribonucleic acid; SD, standard deviation.

Ann Lab Med 2022;42:249~257 https://doi.org/10.3343/alm.2022.42.2.249

© Ann Lab Med