Sample characteristics
Total (N = 40) | Normal (N = 10) | Mild leukopenia (N = 10) | Moderate leukopenia (N = 10) | Severe leukopenia (N = 10) | |
---|---|---|---|---|---|
Age, median (IQR) | 64 (33-76) | 47 (33-71) | 77 (64-78) | 62 (62-73) | 33 (33-65) |
Male, N (%) | 21 (52.5) | 6 (60) | 6 (60) | 2 (20) | 7 (70) |
Diagnosis, N (%) | |||||
AML | 18 (45) | 3 (30) | 1 (10) | 7 (70) | 7 (70) |
Lymphoma |
5 (12.5) | - | 3 (30) | 2 (20) | - |
PCM | 4 (10) | 1 (10) | 1 (10) | - | 2 (20) |
MDS | 3 (7.5) | - | 3 (30) | - | - |
ALL | 1 (2.5) | - | - | 1 (10) | - |
CML | 1 (2.5) | 1 (10) | - | - | - |
AA | 1 (2.5) | - | - | - | 1 (10) |
No hematologic diseases |
7 (17.5) | 5 (50) | 2 (20) | - | - |
WBC counts, median (IQR) | 2,215 (610-4,863) | 7,010 (5,708-7,798) | 2,840 (2,615-3,400) | 1,710 (1,125-1,930) | 60 (50-190) |
WBC differentials |
|||||
Five differentials | 26 (65) | 10 (100) | 2 (20) | 4 (40) | 10 (100) |
Blasts | 3 (7.5) | - | 3 (30) | - | - |
Immature granulocytes |
8 (20) | - | 5 (50) | 3 (30) | - |
nRBCs | 1 (2.5) | - | 1 (10) | - | - |
Lymphocytes, variant form | 9 (22.5) | - | 6 (60) | 3 (30) | - |
*Lymphoma included follicular lymphoma (N=3) and diffuse large B cell lymphoma (N=2); †No hematologic diseases included bone marrow donors (N=2), liver disease (N=2), cardiac disease (N=2), and breast cancer (N=1); ‡The number of WBC differentials included all numbers of five overlapping differentials, blasts, immature granulocytes, nRBC, and variant lymphocytes; §Immature granulocytes included promyelocytes, myelocytes, and metamyelocytes.
Abbreviations: N, number; IQR, interquartile range; AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; PCM, plasma cell myeloma; MDS, myelodysplastic syndrome; CML, chronic myeloid leukemia; AA, aplastic anemia; WBC, white blood cell; nRBCs, nucleated red blood cells.
© Ann Lab Med