Fig. 1. PHB2 IHCS of BM sections obtained from initial diagnostic stage of CN-AML. PHB2 protein expression was semi-quantitatively scored based on IHCS diffuseness (0–5) and intensity (0–3) in BM sections from CN-AML patients. (A) grade 0 (diffuseness 0 + intensity 0), (B) grade 3 (2 + 1), (C) grade 6 (4 + 2), and (D) grade 8 (5 + 3) (IHCS, ×400 magnification).
Abbreviations: PHB2, prohibitin 2; IHCS, immunohistochemical staining; BM, bone marrow; CN-AML, cytogenetically normal acute myeloid leukemia.

Ann Lab Med 2022;42:585~589 https://doi.org/10.3343/alm.2022.42.5.585