OPEN ACCESS pISSN 2234-3806
eISSN 2234-3814

Table. 1.

Table. 1.

Results of MU estimation using different calculation methods

Analytes QC level 1 QC level 2 No. of reagent lots used


Urel_tot (%) Urel_sub (%) %Difference* Urel_tot (%) Urel_sub (%) %Difference
Albumin 2.944 2.881 0.063 2.565 2.479 0.086 3
ALP 4.259 4.013 0.245 4.085 3.59 0.495 3
ALT 8.01 7.995 0.015 2.591 2.573 0.018 2
AST 5.425 5.382 0.043 2.939 2.908 0.031 3
HDL 4.655 4.165 0.49 5.348 4.523 0.825 3
LDL 4.414 4.312 0.101 3.926 3.837 0.089 2
Total cholesterol 3.554 3.491 0.064 3.567 3.485 0.083 4
Creatinine 5.847 5.813 0.034 4.345 4.334 0.011 3
Glucose 2.159 2.085 0.073 2.144 2.068 0.076 4
Total protein 2.359 2.311 0.048 2.29 2.263 0.028 4
Triglyceride 2.581 2.579 0.002 2.534 2.532 0.002 3
K 1.538 1.538 7.13E-05 1.284 1.282 0.002 2
Na 1.557 1.525 0.032 1.368 1.347 0.021 4
BUN 4.366 4.306 0.06 3.477 3.458 0.02 4
Mean 4.752 4.606 0.146 3.575 3.342 0.232 2.9
Median 4.414 4.165 0.064 3.567 3.485 0.086 3
Min (analyte) 2.944 2.881 1.45E-02 2.534 2.532 0.018 2
K Triglyceride
Max (analyte) 4.655 4.165 0.49 5.348 4.523 0.825 4
HDL HDL

*%Difference = % Urel_tot – %Sub Urel_sub

Abbreviations: MU, measurement uncertainty; QC, quality control; Urel_tot, expanded relative uncertainty (coverage factor, k=2) calculated regardless of reagent lot change, akin to CV; Urel_sub, expanded relative uncertainty (coverage factor, k=2) with obtained values from each subgroup, akin to CV; ALP, alkaline phosphatase; K, potassium; Na, sodium; BUN, blood urea nitrogen.

Ann Lab Med 2022;42:630~637 https://doi.org/10.3343/alm.2022.42.6.630

© Ann Lab Med