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Fig. 2.

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Fig. 2. Schematic illustration of reagent lot change simulation using artificial IQC data. (A) Process of generating baseline and shifted artificial IQC datasets. (B) MU estimation with the generated datasets by different calculation methods.
Abbreviations: IQC, internal quality control; MU, measurement uncertainty; m0–10, arithmetic mean of baseline and shifted datasets; utot, standard uncertainty calculated regardless of a reagent lot change; usub, combined uncertainty calculated using values obtained from each subgroup; ubase, standard uncertainty of the baseline data; ushift, standard uncertainty of the shifted data; x, measurand quantity value; n, total number of values; ni, number of values in the ith group; m, number of groups of values.
Ann Lab Med 2022;42:630~637

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