OPEN ACCESS pISSN 2234-3806
eISSN 2234-3814

Table. 1.

Characteristics of patients with AML with RUNX1::RUNX1T1

Characteristics Without SM-AHN (N = 19) With SM-AHN (N = 4) P
Age (yr)
Median (range) 43 (4–74) 38.5 (8–56) 0.683
Sex, N (%)
Male 12 (63.2) 2 (50) 1.000
Female 7 (36.8) 2 (50)
Hb (g/L)
Median (range) 84 (52–116) 86 (69–101) 0.892
Leukocytes ( × 109/L)
Median (range) 5,810 (750–26,610) 10,540 (4,690–29,930) 0.366
Absolute neutrophil count ( × 109/L)
Median (range) 1,243 (66–13,017) 730 (125–1,373) 0.457
Platelets ( × 109/L)
Median (range) 57 (22–110) 61 (16–81) 0.953
KIT variant, N (%) 3 (15.8) 3 (75) 0.040
D816V 2 (10.5) 2 (50)
Other 1 (5.3) 1 (25)
Outcome
Follow-up, months, median (range) 22 (2–68) 33 (11–70) 0.494
Hematopoietic stem cell transplantation, N (%) 11 (57.9) 4 (100) 0.257
Death, N (%) 2 (11.1) 1 (25.0) 0.470

Abbreviations: AML, acute myeloid leukemia; SM-AHN, systemic mastocytosis with associated hematological neoplasm.

Ann Lab Med 2022;42:678~682 https://doi.org/10.3343/alm.2022.42.6.678

© Ann Lab Med