Fig. 2. Heatmap and hierarchical clustering of the 31 most significant DEGs by CHIP status. CHIP-positive samples (purple; N=6) are segregated from CHIP-negative samples (light purple; N=6), except for an outlier. All genes listed had a log₂ fold change >1 or <–1 and adjusted P<0.05 in DESeq2 (v3.5e) analysis. The heatmap color range is from positive (red) to negative (blue) Z-score values.
Abbreviations: DEG, differentially expressed gene; CHIP, clonal hematopoiesis of indeterminate potential.

Ann Lab Med 2023;43:145~152 https://doi.org/10.3343/alm.2023.43.2.145