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Fig. 3.

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Fig. 3. Enrichment of the neutrophil degranulation pathway in CHIP-positive samples. (A) Differential expression of neutrophil/innate immunity-related genes, compared between individuals with CHIP mutations and those without. Data are presented as the median and interquartile range. (B) Upper panel: enrichment plot of the neutrophil degranulation pathway shown as a snapshot of the GSEA. Lower panel: heatmap showing the expression of genes belonging to the set with the annotation of genes ordered. *P<0.05, **P<0.01.
Abbreviations: CHIP, clonal hematopoiesis of indeterminate potential; GSEA, gene set enrichment analysis.
Ann Lab Med 2023;43:145~152 https://doi.org/10.3343/alm.2023.43.2.145

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