pISSN 2234-3806eISSN 2234-3814
Table. 2.
ORL and BA analyses before and after recalibration
| Assays compared | Before recalibration | After recalibration | ||||||
|---|---|---|---|---|---|---|---|---|
| Slope (95% CI) | Intercept (95% CI) | R2 | Percentage difference (95% CI) | Slope (95% CI) | Intercept (95% CI) | R2 | Percentage difference (95% CI) | |
| Roche vs. ID-LC–MS/MS | 1.54 (1.50, 1.57) | -43.7 (-88.0, 0.5) | 0.99 | 49.9 (46.9, 52.8) |
1.06 (1.04, 1.08) | -58.1 (-88.4, -27.8) | 0.99 | -1.5 (-3.6, 0.6) |
| Mindray vs. ID-LC–MS/MS | 1.62 (1.58, 1.66) | -234.4 (-284.1, -184.8) | 0.99 | 32.2 (26.9, 35.7) | 1.06 (1.04, 1.08) | -76.6 (-108.9, -44.3) | 0.99 | -3.0 (-5.1, 0.9) |
| Snibe vs. ID-LC–MS/MS | 1.88 (1.82, 1.94) | -67.2 (-154.3, -19.8) | 0.98 | 81.7 (77.3, 86.1) |
1.03 (1.00, 1.07) | -25.4 (-72.7, 22.0) | 0.98 | 0.50 (-1.9, 2.9) |
| Beckman vs. ID-LC–MS/MS | 1.05 (1.03, 1.07) | -108.7 (-138.8, -78.5) | 0.99 | -8.6 (-11.2, -7.0) | 1.04 (1.02, 1.06) | -78.6 (-105.3, -48.8) | 0.99 | -6.0 (-7.9, -4.1) |
| Abbott vs. ID-LC–MS/MS | 1.56 (1.52, 1.59) | -161.0 (-212.7, -109.2) | 0.99 | 35.4 (31.6, 39.3) |
1.09 (1.07, 1.12) | -74.1 (-110.5, -37.9) | 0.99 | 0.01 (-2.3, 2.3) |
| Siemens vs. ID-LC–MS/MS | 1.17 (1.14, 1.21) | -148.0 (-198.6, -97.3) | 0.98 | 0.2 (-3.5, 2.3) | 1.07 (1.03, 1.10) | -59.5 (-106.0, -13.9) | 0.98 | 1.2 (-1.2, 3.7) |
*Data were normally distributed (Kolmogorov-Smirnov test) and used mean (relative) difference, whereas others used median relative difference.
Abbreviations: ORL, ordinary linear regression; BA, Bland-Altman; CI, confidence interval; ID-LC–MS/MS, isotope dilution liquid chromatography-tandem mass spectrometry.
Ann Lab Med 2023;43:345~354 https://doi.org/10.3343/alm.2023.43.4.345
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