OPEN ACCESS pISSN 2234-3806
eISSN 2234-3814

Table. 2.

Table. 2.

ORL and BA analyses before and after recalibration

Assays compared Before recalibration After recalibration


Slope (95% CI) Intercept (95% CI) R2 Percentage difference (95% CI) Slope (95% CI) Intercept (95% CI) R2 Percentage difference (95% CI)
Roche vs. ID-LC–MS/MS 1.54 (1.50, 1.57) -43.7 (-88.0, 0.5) 0.99 49.9 (46.9, 52.8)* 1.06 (1.04, 1.08) -58.1 (-88.4, -27.8) 0.99 -1.5 (-3.6, 0.6)
Mindray vs. ID-LC–MS/MS 1.62 (1.58, 1.66) -234.4 (-284.1, -184.8) 0.99 32.2 (26.9, 35.7) 1.06 (1.04, 1.08) -76.6 (-108.9, -44.3) 0.99 -3.0 (-5.1, 0.9)
Snibe vs. ID-LC–MS/MS 1.88 (1.82, 1.94) -67.2 (-154.3, -19.8) 0.98 81.7 (77.3, 86.1)* 1.03 (1.00, 1.07) -25.4 (-72.7, 22.0) 0.98 0.50 (-1.9, 2.9)
Beckman vs. ID-LC–MS/MS 1.05 (1.03, 1.07) -108.7 (-138.8, -78.5) 0.99 -8.6 (-11.2, -7.0) 1.04 (1.02, 1.06) -78.6 (-105.3, -48.8) 0.99 -6.0 (-7.9, -4.1)
Abbott vs. ID-LC–MS/MS 1.56 (1.52, 1.59) -161.0 (-212.7, -109.2) 0.99 35.4 (31.6, 39.3)* 1.09 (1.07, 1.12) -74.1 (-110.5, -37.9) 0.99 0.01 (-2.3, 2.3)
Siemens vs. ID-LC–MS/MS 1.17 (1.14, 1.21) -148.0 (-198.6, -97.3) 0.98 0.2 (-3.5, 2.3) 1.07 (1.03, 1.10) -59.5 (-106.0, -13.9) 0.98 1.2 (-1.2, 3.7)

*Data were normally distributed (Kolmogorov-Smirnov test) and used mean (relative) difference, whereas others used median relative difference.

Abbreviations: ORL, ordinary linear regression; BA, Bland-Altman; CI, confidence interval; ID-LC–MS/MS, isotope dilution liquid chromatography-tandem mass spectrometry.

Ann Lab Med 2023;43:345~354 https://doi.org/10.3343/alm.2023.43.4.345

© Ann Lab Med