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Fig. 1.

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Fig. 1. Schematic of the electrophoretic process for POC testing of anemia and Hb variants. (A) A whole blood specimen (red) is mixed with a standard calibrator (blue) and electrophoresed on the cellulose acetate paper. (B) Within 2.5 minutes, the Hb is separated from the standard. A ML ANN is used to determine the Hb concentration and anemia status. (C) Within 8 minutes, the Hb is separated into the different variants, and major variants are determined (Adapted from An, et al. [27].).
Abbreviations: POC, point-of-care; ML machine learning; ANN, artificial neural network.
Ann Lab Med 2023;43:401~407

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