pISSN 2234-3806eISSN 2234-3814
Table. 3.
Transplanted culture-positive HSC products and patient outcomes
| Case number | Diagnosis | Sample type | Microbial culture | Source/step of contamination | Prophylactic antibiotics | Evidence of infection |
Outcome |
|---|---|---|---|---|---|---|---|
| 1 | Neuroblastoma, stage IV | Auto-PBSC | Collection/processing | Teicoplanin, ticarcillin/clavulanic acid, gentamicin | Not apparent | Engrafted | |
| 2 | Severe aplastic anemia | Allo-BM | Culture preparation | Acyclovir, cefepime, teicoplanin, micafungin | Not apparent | Engrafted | |
| 3 | Acute myeloid leukemia | Allo-PBSC | Culture preparation | Acyclovir, cefepime, micafungin | Not apparent | Engrafted | |
| 4 | Acute myeloid leukemia | Allo-PBSC | Culture preparation | Acyclovir, voriconazole | Not apparent | Engrafted |
*Evidence of infection was assessed based on body temperature, blood pressure, respiratory rate, pulse rate, and the serum C-reactive protein concentration within 24 hours after infusion.
Abbreviations: HSC, hematopoietic stem cell; PBSC, peripheral blood stem cell; BM, bone marrow.
Ann Lab Med 2023;43:477~484 https://doi.org/10.3343/alm.2023.43.5.477
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