pISSN 2234-3806eISSN 2234-3814
Table. 3.
Performance of the three scoring systems for the prediction of patients with TMA due to severe ADAMTS13 deficiency assessed to be at high risk
| Scoring system | Sensitivity, % (95% CI) | Specificity, % (95% CI) | NPV, % (95% CI) | PPV, % (95% CI) | Accuracy, % |
|---|---|---|---|---|---|
| FTMA-S | 72.7 (57.2–85.0) | 54.5 (44.2–64.4) | 82.1 (70.8–90.4) | 41.0 (30.0–52.7) | 60.0 |
| PLASMIC-S | 81.8 (67.3–91.8) | 82.2 (73.3–89.1) | 91.2 (83.4–96.1) | 66.7 (52.5–78.9) | 82.1 |
| B-S | 4.6 (0.7–15.5) | 98.0 (93.0–99.7) | 70.2 (61.9–77.6) | 50.0 (8.3–91.7) | 69.7 |
Abbreviations: TMA, thrombotic microangiopathy; ADAMTS13, a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13; FTMA-S, French TMA score; PLASMIC-S, PLASMIC score; B-S, BENTLEY score; CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value.
Ann Lab Med 2023;43:485~492 https://doi.org/10.3343/alm.2023.43.5.485
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