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Table. 5. Table 5

Response to TPE and mortality in 44 patients with TMA due to severe ADAMTS13 deficiency according to the PLASMIC-S

Variables	PLASMIC-S risk assessment		P^*

	Low-to-intermediate risk (N=8)	High risk (N=36)
ITR, N (%)	4 (50.0)	31 (86.1)	0.042
N of TPE for ITR, median (range)	8.0 (7.0–9.0)	5.0 (1.0–8.0)	0.001
Death, N (%)	4 (50.0)	6 (16.7)	0.064

*P-values were obtained from the Mann–Whitney U-test for the comparison of continuous variables and the Fisher’s exact test for the comparison of categorical variables.

Abbreviations: TPE, therapeutic plasma exchange; TMA, thrombotic microangiopathy; ADAMTS13, a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13; PLASMIC-S, PLASMIC score; ITR, initial treatment response.

Ann Lab Med 2023;43:485~492 https://doi.org/10.3343/alm.2023.43.5.485