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Table. 1.

Table. 1.

Comparison of cystatin C-based eGFR equations used in the current study

Name Reference Year Age (yr) Sex cysC (mg/L) Equation
Gentianeq [21] 2007 - - - 79.901/ Gentiancys1.4389
CKD-EPIcys [8] 2011 - Male ≤ 0.8 133 × (cysC/0.8)−0.499 × 0.996age
> 0.8 133 × (cysC/0.8)−1.328 × 0.996age
- Female ≤ 0.8 133 × (cysC/0.8)−0.499 × 0.996age × 0.932
> 0.8 133 × (cysC/0.8)−1.328 × 0.996age × 0.932
CAPAeq [17] 2014 - - - 130 × cysC−1.069 × age−0.117−7
FASeq* [18] 2017 ≤ 40 - - 107.3/(cysC/Qcys)
40 < age < 70 107.3/(cysC/Qcys) × 0.988(age−40)
≥ 70 107.3/(cysC/Qcys) × 0.988(age−40)
EKFCcys [19] 2023 ≤ 40 - - 107.3/(cysC/Qcys)
40 < age < 50 107.3/(cysC/Qcys) × 0.990(age−40)
≥ 50 107.3/(cysC/Qcys) × 0.990(age−40)

*For Qcys of FASeq, 0.82 mg/L for ages <70 years and 0.95 mg/L for ages ≥70 years are used; For Qcys of EKFCcys, 0.83 mg/L for ages <50 years and 0.83+ 0.005×(age−50) mg/L for ages ≥50 years are used.

Abbreviations: eGFR, estimated glomerular filtration rate; CKD-EPIcys, CKD-EPI cystatin C equation; CAPAeq, Caucasian, Asian, pediatric, and adult participants equation; FASeq, full age spectrum equation; Gentianeq, equation of Gentian manufacturer recommendation; Gentiancys, Gentian cystatin C immunoassay; cysC, cystatin C; Qcys, population-normalized cystatin C.

Ann Lab Med 2023;43:565~573 https://doi.org/10.3343/alm.2023.43.6.565

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