Passing–Bablok regression equations comparing immunoassays (Y-axis) with LC-MS/MS (X-axis) and direct (Y-axis) with extraction (X-axis) assays of Beckman and Siemens
Variable | Abbott-D vs. LC-MS/MS |
Beckman-D vs. LC-MS/MS |
Siemens-D vs. LC-MS/MS |
Beckman-E vs. LC-MS/MS |
Siemens-E vs. LC-MS/MS |
Beckman-D vs. Beckman-E |
Siemens-D vs. Siemens-E |
---|---|---|---|---|---|---|---|
Slope (95% CI) | 1.42 (1.39–1.45) | 5.42 (4.85–6.19) | 3.02 (2.60–3.60) | 1.41 (1.37–1.46) | 1.55 (1.47–1.63) | 3.64 (3.23–4.07) | 1.76 (1.59–1.98) |
Intercept (95% CI) | 0.80 (–0.33–1.57) | 109.61 (88.11–127.15) | 139.10 (119.75–155.88) | 25.11 (23.29–27.45) | 26.29 (23.31–28.52) | 29.38 (9.44–61.43) | 100.96 (86.64–120.39) |
Spearman r (95% CI) | 0.965 (0.957–0.972) |
0.755 (0.705–0.798) |
0.897 (0.873–0.916) |
0.922 (0.904–0.937) |
0.922 (0.904–0.937) |
0.752 (0.701–0.796) |
0.900 (0.878–0.919) |
*Reference method (X-axis).
†
Abbreviations: LC-MS/MS, liquid chromatography-tandem mass spectrometry; CI, confidence interval; D, direct assay; E, extraction assay.
© Ann Lab Med