OPEN ACCESS pISSN 2234-3806
eISSN 2234-3814

Table. 2.

Passing–Bablok regression equations comparing immunoassays (Y-axis) with LC-MS/MS (X-axis) and direct (Y-axis) with extraction (X-axis) assays of Beckman and Siemens

Variable Abbott-D vs. LC-MS/MS* Beckman-D vs. LC-MS/MS* Siemens-D vs. LC-MS/MS* Beckman-E vs. LC-MS/MS* Siemens-E vs. LC-MS/MS* Beckman-D vs. Beckman-E* Siemens-D vs. Siemens-E*
Slope (95% CI) 1.42 (1.39–1.45) 5.42 (4.85–6.19) 3.02 (2.60–3.60) 1.41 (1.37–1.46) 1.55 (1.47–1.63) 3.64 (3.23–4.07) 1.76 (1.59–1.98)
Intercept (95% CI) 0.80 (–0.33–1.57) 109.61 (88.11–127.15) 139.10 (119.75–155.88) 25.11 (23.29–27.45) 26.29 (23.31–28.52) 29.38 (9.44–61.43) 100.96 (86.64–120.39)
Spearman r (95% CI) 0.965 (0.957–0.972) 0.755 (0.705–0.798) 0.897 (0.873–0.916) 0.922 (0.904–0.937) 0.922 (0.904–0.937) 0.752 (0.701–0.796) 0.900 (0.878–0.919)

*Reference method (X-axis).

P<0.0001.

Abbreviations: LC-MS/MS, liquid chromatography-tandem mass spectrometry; CI, confidence interval; D, direct assay; E, extraction assay.

© Ann Lab Med