pISSN 2234-3806eISSN 2234-3814
Table. 1.
Baseline clinical characteristics according to the presence of AVS
| Characteristics |
AVS (N=125) | Age- and sex-matched control (N=62) | |
|---|---|---|---|
| Demographics | |||
| Age, yrs | 72.9±8.4 | 71.9±8.5 | 0.437 |
| Female sex, N (%) | 58 (46.4) | 27 (43.5) | 0.832 |
| Body mass index, kg/m2 | 25.2±3.2 | 23.9±3.1 | 0.013 |
| Systolic blood pressure, mmHg | 133.0±18.6 | 138.1±17.4 | 0.073 |
| Diastolic blood pressure, mmHg | 73.2±14.3 | 73.8±13.7 | 0.768 |
| Cardiovascular risk factors | |||
| Hypertension | 102 (81.6) | 37 (59.7) | 0.002 |
| Diabetes mellitus | 52 (41.6) | 17 (27.4) | 0.083 |
| Dyslipidemia | 76 (60.8) | 28 (45.2) | 0.061 |
| Coronary artery disease | 3 (7.5) | 5 (6.7) | 0.999 |
| Chronic kidney disease | 18 (14.4) | 3 (4.8) | 0.088 |
| Previous stroke | 18 (14.4) | 3 (4.8) | 0.088 |
| Medication history, N (%) | |||
| Antiplatelet | 58 (46.4) | 16 (25.8) | 0.011 |
| RAS blocker | 72 (57.6) | 32 (51.6) | 0.536 |
| β-blocker | 47 (37.6) | 15 (24.2) | 0.095 |
| Calcium channel blocker | 61 (48.8) | 17 (27.4) | 0.008 |
| Statins | 77 (61.6) | 32 (51.6) | 0.252 |
| Hypoglycemics | 45 (36.0) | 13 (21.0) | 0.054 |
| Anticoagulant | 19 (15.2) | 12 (19.4) | 0.610 |
| Major laboratory findings | |||
| Hemoglobin, g/L | 124 (108–138) | 139 (128–146) | <0.001 |
| Platelet count, ×109/L | 0.218 (0.173–0.254) | 0.231 (0.169–0.263) | 0.287 |
| GFR, mL/min/1.73 m2 | 78.0 (59.0–89.5) | 85.0 (77.0–94.0) | 0.002 |
| Fasting glucose, mmol/L | 6.08 (5.38–7.41) | 5.99 (5.44–6.77) | 0.341 |
| Triglycerides, mmol/L | 1.29 (0.94–1.98) | 1.29 (0.85–1.74) | 0.518 |
| HDL, mmol/L | 1.17 (1.00–1.42) | 1.40 (1.19–1.53) | 0.007 |
| LDL, mmol/L | 2.15 (1.58–2.90) | 2.27 (1.71–3.33) | 0.208 |
| C-reactive protein, mg/L | 16 (7–77) | 8 (5–15) | 0.036 |
| NT-proBNP, pmol/L | 28.91 (8.97–181.01) | 12.69 (5.31–40.83) | 0.070 |
*Categorical variables are presented as numbers (percentages). Continuous variables are presented as the mean±SD or median (interquartile range), as appropriate.
†
Abbreviations: AVS, aortic valve sclerosis; RAS, renin–angiotensin system; GFR, estimated glomerular filtration rate using the Chronic Kidney Disease Epidemiology Collaboration equation; NT-proBNP, N-terminal prohormone of brain natriuretic peptide.
Ann Lab Med 2024;44:279~288 https://doi.org/10.3343/alm.2023.0268
© Ann Lab Med