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Table. 2.

Table. 2.

Proportions of participants with CHIP (defined as VAF ≥0.5%, ≥1%, or ≥2%) in the patient and control group (original and IPTW cohorts)

Study cohort Group VAF≥0.5% VAF≥1% VAF≥2%
N (%) P* N (%) P N (%) P
Original cohort Control (N=62) 30 (48.4) 0.680 13 (21.0) 0.020 4 (6.5) 0.028
AVS (N=125) 66 (52.8) 49 (39.2) 25 (20.0)
IPTW cohort Control (N=83) 42 (50.6) 0.898 17 (20.5) 0.030 4 (4.8) 0.001
AVS (N=98) 52 (53.1) 38 (38.8) 20 (20.4)

*P<0.05.

Abbreviations: CHIP, clonal hematopoiesis indeterminate potential; VAF, variant allele frequency; IPTW, inverse-probability treatment weighting; AVS, aortic valve sclerosis.

Ann Lab Med 2024;44:279~288 https://doi.org/10.3343/alm.2023.0268

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