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Table. 1. Characteristics of COVID-19 patients with mild, moderate, and severe clinical symptoms
Characteristic Total (N=90) COVID-19 clinical symptoms P
Mild (N=30) Moderate (N=30) Severe (N=30)
Age (yrs), mean±SD 45.8±13.9 35.0±11.2 53.2±13.3 49.3±10.0 <0.001*
Sex, N (%) 0.002
Male 52 (57.8) 25 (83.3) 13 (43.3) 14 (46.7)
Female 38 (42.2) 5 (16.7) 17 (56.7) 16 (53.3)
Condition, N (%) <0.001
With comorbidities 41 (45.6) 5 (16.7) 19 (63.3) 17 (56.7)
Without comorbidities 49 (54.4) 25 (83.3) 11 (36.7) 13 (43.3)
Outcome, N (%) <0.001
Survived 69 (76.7) 30 (100.0) 22 (73.3) 17 (56.7)
Did not survive 21 (23.3) N/A 8 (26.7) 13 (43.3)
Laboratory findings
SpO2 (%), median (range) 97 (60–100) 99 (97–100) 97 (94–99) 76.5 (60–92) 0.001
PLT count (×103/µL), mean±SD 308.1±145.4 N/A 309.6±153.1 306.5±140.0 0.935§
Monocyte count (×103/µL), median (range) 0.8 (0.1–3.3) N/A 0.7 (0.1–2.0) 0.9 (0.2–3.3) 0.084||
Coagulation parameters
PT (sec), median (range) 11.1 (9.4–21.6) N/A 11 (9.7–18.3) 11.1 (9.4–21.6) 0.750||
APTT (sec), median (range) 28.8 (18.2–100) N/A 27.9 (18.2–100) 29.3 (18.5–82.2) 0.988||
D-dimer (ng/mL), median (range) 1,980 (380–19,050) N/A 1,290 (380–5,360) 2,825 (540–19,050) 0.028||

The results are expressed as mean±SD, median (range), or N (%). The data were analyzed using ANOVA (*), Chi-square test (), Kruskal–Wallis test (), independent t-test (§), or Mann–Whitney U test (||). Significance was set at P<0.05.

Abbreviations: COVID-19, coronavirus disease; SpO2, oxygen saturation; PLT, platelets; PT, prothrombin time; APTT, activated partial thromboplastin time; N/A, not applicable.

Ann Lab Med 2024;44:392~400 https://doi.org/10.3343/alm.2023.0395

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