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Table. 1.

Table. 1.

Detection of a high-dose hook effect using 1:10, 1:50, and 1:400 dilutions

Sample number Neat
(nmol/L)
1:10 dilution
(nmol/L)
Hook effect detected
(1:10; >168.54 nmol/L)
1:50 dilution
(nmol/L)
Hook effect detected
(1:50; >168.54 nmol/L)
1:400 dilution
(nmol/L)
1 48.89 125.79 No hook effect 154.83 No hook effect
2 41.63 1,049.21 Detected 2,412.81 Detected
3 10.15 274.04 Detected 2,901.46 Detected
4 85.34 74.78 No hook effect 85.45 No hook effect
5 55.85 197.98 Detected 247.36 Detected
6 64.27 >1,685.40 Detected 2,429.38 Detected
7 42.74 >1,685.40 Detected >8,426.97 Detected 21,166.57
8 25.99 80.62 No hook effect 115.79 No hook effect
9 110.28 1,140.84 Detected 1,316.69 Detected
10 43.51 >1,685.40 Detected 6,093.54 Detected
11 20.08 732.08 Detected 5,770.34 Detected
12 89.61 111.97 No hook effect 110.79 No hook effect
13 20.31 282.58 Detected 530.56 Detected
14 30.52 >1,685.40 Detected >8,426.97 Detected 31,265.56
15 34.17 459.78 Detected 824.10 Detected
16 28.51 >1,685.40 Detected >8,426.97 Detected 12,656.46
17 34.17 >1,685.40 Detected >8,426.97 Detected 15,379.49
18 9.56 901.91 Detected >8,426.97 Detected 21,466.80
19 28.60 1,326.57 Detected 6,596.07 Detected
20 >168.54 >1,685.40 Detected 3,221.52 Detected
21 31.82 1,133.48 Detected 5,771.01 Detected
22 48.18 952.13 Detected 2,553.48 Detected
23 16.34 384.89 Detected 3,048.03 Detected
24 61.57 1,084.78 Detected 1,499.72 Detected
25 8.31 302.87 Detected 2,155.17 Detected
26 28.19 413.99 Detected 613.09 Detected
27 >168.54 >1,685.40 Detected 2,070.11 Detected
28 7.66 265.34 Detected 390.22 Detected
29 10.99 75.96 No hook effect 152.87 No hook effect
30 63.43 >1,685.40 Detected 6,177.75 Detected
31 96.24 395.45 Detected 431.01 Detected
32 31.87 552.81 Detected 1,724.72 Detected
33 77.53 1,501.52 Detected 2,090.51 Detected
34 108.71 224.44 Detected 259.21 Detected
35 >168.54 1,316.69 Detected 1,617.02 Detected
Ann Lab Med 2024;44:367~370 https://doi.org/10.3343/alm.2023.0427

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