Fig. 1. Subgroup analyses in MDS-SF3B1^WHO. Kaplan–Meier curves of overall survival were plotted according to (A) type of SF3B1 variants (K700E alone vs. others), (B) VAF of SF3B1 variants (5%≤VAF<10% vs. VAF≥10%), and (C) RUNX1 co-mutation (wild-type vs. mutated). HRs and 95% CIs were calculated using Cox proportional-hazards models adjusted for sex, age, ontogeny, treatment, type of SF3B1 variants, VAF of SF3B1 variants, and RUNX1 co-mutation. The HR is shown with the 95% CI in parentheses.
Abbreviations: VAF, variant allele frequency; HR, hazard ratio; CI, confidence interval.

Ann Lab Med 2025;45:36~43 https://doi.org/10.3343/alm.2024.0079