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Table. 1. Breakpoints proposed in CLSI, EUCAST, and this study
Antimicrobial agent MIC breakpoints (µg/mL) Zone diameter breakpoints (mm)
CLSI EUCAST EUCAST This study
S≤ I R≥ S≤ R> S≥ R< S≥ ATU R≤
Penicillin 0.5 1 2 - - - - 15 - 14
Cefoxitin 16 32 64 - - - - 22 19–21 18
Cefotetan 16 32 64 - - - - 23 19–22 18
Imipenem 4 8 16 1 1 29 29 30 27–29 26
Meropenem 4 8 16 1 1 28 28 29 26–28 25
Pip/tazobactam 16 32–64 128 2 2 24 24 25 22–24 21
Clindamycin 2 4 8 4 4 10 10 10 - 9
Moxifloxacin 2 4 8 - - - - 22 19–21 18
Metronidazole 8 16 32 4 4 25 25 25 - 24

Abbreviations: MIC, minimum inhibitory concentration; EUCAST, European Committee on Antimicrobial Susceptibility Testing; Pip, piperacillin; S, susceptible; R, resistant; ATU, area of technical uncertainty; -, not applicable.

Ann Lab Med 2025;45:70~76 https://doi.org/10.3343/alm.2024.0159

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