Download original image
Fig. 1.
Representative FISH and molecular analysis results for various NUP98r. (A) FISH analysis using a NUP98 break-apart probe showed negative (two fusions) and positive (one red, one green, and one fusion) signals in case No. 11. (B) Agarose gel electrophoresis of fusion transcripts between NUP98 and each partner gene (lane 1, internal control using GAPDH [amplicon size, 131 bp], lane 2, fusion transcripts using primer pairs of NUP98 and partner genes). (C) Confirmation of the breakpoint of each fusion transcript via Sanger sequencing.
Abbreviation: NUP98r, NUP98 rearrangement.
© Ann Lab Med