Fig. 3. Examples of chromosome abnormalities via karyotyping and FISH. (A) Karyotype of AML with a monosomal karyotype, with losses of multiple chromosomes, including monosomy 7. (B) del(5q) in a case of AML. FISH using a dual color probe set for EGR1 (5q31) and D5S23 (5p15.2) (one orange signal for EGR1 and two green signals for D5S23).
Abbreviations: EGR1, early growth response 1; D5S23, human D5S23 control region on 5p.

Ann Lab Med 2025;45:133~145 https://doi.org/10.3343/alm.2024.0477