View Full Text
Article as PDF
Print this Page
Export to Citation
YouTube
Google Scholar
Pubmed
PMC
Performance Evaluation of VITEK MS for the Identification of a Wide Spectrum of Clinically Relevant Filamentous Fungi Using a Korean Collection
2021; 41(2): 214-220
Article
Original Article
Ann Lab Med 2012; 32(3): 190-193
Published online May 1, 2012 https://doi.org/10.3343/alm.2012.32.3.190
Copyright © Korean Society for Laboratory Medicine.
Comparison of Serum Zinc Levels Measured by Inductively Coupled Plasma Mass Spectrometry in Preschool Children with Febrile and Afebrile Seizures
Jun-Hwa Lee, M.D.1 and Jeong Hyun Kim, M.D.2
Departments of Pediatrics1 and Laboratory Medicine2, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea
Correspondence to: Jeong Hyun Kim
Department of Laboratory Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, 50 Hapsung-dong, Masan Hoewon-gu, Changwon 630-522, Korea
Tel: +82-55-290-6095
Fax: +82-55-290-6498
E-mail: docto95@nate.com
Received: August 26, 2011; Revised: January 16, 2012; Accepted: February 8, 2012
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Changes in levels of trace elements have been proposed to underlie febrile
seizures. Particularly, low zinc levels have been proposed as related factor of febrile seizure.
In this study, we investigated whether mean serum zinc levels differed between children
with febrile seizure and afebrile seizure.
Methods: Using inductively coupled plasma mass spectrometry, serum zinc levels were
measured in 288 children who had been diagnosed with febrile seizures (N=248) and
afebrile seizures (N=40). Mean serum zinc levels were compared between the 2 groups.
Results: Mean serum zinc level was 60.5±12.7 μg/dL in the febrile seizure group and 68.9
±14.5 μg/dL in the afebrile seizure group. A significant difference in serum zinc levels was
observed between the febrile and afebrile seizure groups (P <0.001).
Conclusions: Zinc levels in children with febrile seizure were significantly lower than those
in children with afebrile seizure.
Keywords: Zinc, Febrile seizure, Mass spectrometry