Letter to the Editor

Ann Lab Med 2019; 39(3): 327-329

Published online May 1, 2019

Copyright © Korean Society for Laboratory Medicine.

FLT3 Internal Tandem Duplication in Patients With Acute Myeloid Leukemia Is Readily Detectable in a Single Next-Generation Sequencing Assay Using the Pindel Algorithm

Borahm Kim, M.D.1, SooJeong Kim, M.D.2, Seung-Tae Lee, M.D.1, Yoo Hong Min, M.D.2, and Jong Rak Choi , M.D.1

Departments of 1Laboratory Medicine and 2Internal Medicine, Yonsei University College of Medicine, Seoul, Korea

Correspondence to: Jong Rak Choi, M.D.
Department of Laboratory Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea
Tel: +82-2-2228-2441,
Fax: +82-2-364-1583,

Received: May 14, 2018; Revised: September 29, 2018; Accepted: December 11, 2018

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Fig. 1.

Correlation of the ITD mutant allele fraction between fragment analysis and the Pindel (0.2.0) algorithm for patients harboring FLT3 ITD mutation.

Abbreviation: ITD, internal tandem duplication.

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