Letter to the Editor
Ann Lab Med 2019; 39(6): 602-605
Published online November 1, 2019 https://doi.org/10.3343/alm.2019.39.6.602
Copyright © Korean Society for Laboratory Medicine.
First Case in Korea of a Patient With Anti-PP1Pk Antibodies: Successful Blood Management via Acute Normovolemic Hemodilution
1Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 2Department of Laboratory Medicine, Soonchunhyang University Hospital Cheonan, Soonchunhyang University College of Medicine, Cheonan, Korea; 3Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea; 4Department of Laboratory Medicine, Chonnam National University Medical School & Hospital, Gwangju, Korea; 5Department of Laboratory Medicine, Dong-A University Hospital, Busan, Korea; 6Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 7Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Correspondence to: Duck Cho, M.D.
Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea
Tel: +82-2-3410-2403, Fax: +82-2-3410-2719, E-mail: email@example.com
Jong-Hwan Lee, M.D.
Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea
Tel: +82-2-3410-1928, Fax: +82-2-3410-0361 E-mail: firstname.lastname@example.org
*These authors equally contributed to this study.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Family study results of the anti-PP1Pk family. (A) P1 phenotype pedigree based on standard serologic method. The proband is indicated by an arrow. (B) Sequencing results were determined on the basis of the combined data from PCR and sequencing of
Abbreviation: dup, duplication.
- Hellberg A, Steffensen R, Yahalom V, Sojka BN, Heier HE, Levene C, et al. Additional molecular bases of the clinically important p blood group phenotype. Transfusion 2003;43:899-907.
- Koda Y, Soejima M, Sato H, Maeda Y, Kimura H. Three-base deletion and one-base insertion of the alpha(1,4)galactosyltransferase gene responsible for the P phenotype. Transfusion 2002;42:48-51.
- Hellberg A, Ringressi A, Yahalom V, Safwenberg J, Reid ME, Olsson ML. Genetic heterogeneity at the glycosyltransferase loci underlying the GLOB blood group system and collection. Br J Haematol 2004;125:528-536.
- Yan L, Zhu F, Xu X, Zantek ND. Molecular basis for p blood group phenotype in China. Transfusion 2004;44:136-138.
- Wang YC, Chang CF, Lin HC, Lin KS, Lin KT, Hung CM, et al. Functional characterisation of a complex mutation in the alpha(1,4)galactosyltransferase gene in Taiwanese individuals with p phenotype. Transfus Med 2011;21:84-89.
- Li X, Diao X, Xia X, Hong X, Zhu F. A novel mutation in
A4GALTwas identified in a Chinese individual with p phenotype. Transfusion 2017;57:215-216.
- Fung MK EA, Spitalnik SL, et al. eds. Technical Manual. 19th ed. Bethesda, Maryland: American Association of Blood Banks, 2018; 2018:286-290.
- Matot I, Scheinin O, Jurim O, Eid A. Effectiveness of acute normovolemic hemodilution to minimize allogeneic blood transfusion in major liver resections. Anesthesiology 2002;97:794-800.
- Nadler SB, Hidalgo JH, Bloch T. Prediction of blood volume in normal human adults. Surgery 1962;51:224-232.