Article

Brief Communication

Ann Lab Med 2022; 42(2): 268-273

Published online March 1, 2022 https://doi.org/10.3343/alm.2022.42.2.268

Copyright © Korean Society for Laboratory Medicine.

Serotype Distribution and Antimicrobial Resistance of Salmonella Isolates in Korea between 2016 and 2017

Si Hyun Kim, Ph.D.1,* , Gyung-Hye Sung, Ph.D.2,* , Eun Hee Park, Ph.D.2 , In Yeong Hwang, Ph.D.2 , Gyu Ri Kim, Ph.D.3 , Sae Am Song, M.D.3 , Hae Kyung Lee, M.D.4 , Young Uh, M.D.5 , Young Ah Kim, M.D.6 , Seok Hoon Jeong, M.D.7 , Jong Hee Shin, M.D.8 , Kyeong Seob Shin, M.D.9 , Jaehyeon Lee, M.D.10 , Joseph Jeong, M.D.11 , Young Ree Kim, M.D.12 , Dongeun Yong, M.D.13 , Miae Lee, M.D.14 , Yu Kyung Kim, M.D.15 , Nam Hee Ryoo, M.D.16 , Seungok Lee, M.D.17 , Jayoung Kim, M.D.18 , Sunjoo Kim, M.D.19 , Hyun Soo Kim, M.D.20 , and Jeong Hwan Shin, M.D.3,21

1Department of Clinical Laboratory Science, Semyung University, Jecheon, Korea; 2Busan Institute of Health and Environment, Busan, Korea; 3Department of Laboratory Medicine, Inje University College of Medicine, Busan, Korea; 4Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea; 5Department of Laboratory Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea; 6Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea; 7Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea; 8Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea; 9Department of Laboratory Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea; 10Department of Laboratory Medicine, Chonbuk National University Medical School, Jeonju, Korea; 11Department of Laboratory Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea; 12Department of Laboratory Medicine, School of Medicine, Jeju National University, Jeju, Korea; 13Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea; 14Department of Laboratory Medicine, Ewha Womans University College of Medicine, Seoul, Korea; 15Department of Laboratory Medicine, School of Medicine, Kyungpook National University, Daegu, Korea; 16Department of Laboratory Medicine, Keimyung University School of Medicine, Daegu, Korea; 17Department of Laboratory Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea; 18Department of Laboratory Medicine, International St. Mary’s Hospital, The Catholic Kwandong University College of Medicine, Incheon, Korea; 19Department of Laboratory Medicine, Gyeongsang National University College of Medicine, Jinju, Korea; 20Department of Laboratory Medicine, Hallym University College of Medicine, Hwaseong, Korea; 21Paik Institute for Clinical Research, Inje University, Busan, Korea

Correspondence to: Jeong Hwan Shin, M.D., Ph.D.
Department of Laboratory Medicine, Busan Paik Hospital, Inje University College of Medicine, 75 Bokji-ro, Busanjin-gu, Busan 47392, Korea
Tel: +82-51-890-6475
Fax: +82-51-893-1562
E-mail: jhsmile@paik.ac.kr

* These authors contributed equally to this work.

Received: January 21, 2021; Revised: March 23, 2021; Accepted: September 16, 2021

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Salmonella is one of the major causes of food-borne infections. We investigated the serotype distribution and antimicrobial resistance of Salmonella isolates collected in Korea between January 2016 and December 2017. In total, 669 Salmonella isolates were collected from clinical specimens at 19 university hospitals. Serotyping was performed according to the Kauffmann–White scheme, and antimicrobial susceptibility was tested using Sensititre EUVSEC plates or disk diffusion. Among the strains, C (39.8%) and B (36.6%) were the most prevalent serogroups. In total, 51 serotypes were identified, and common serotypes were S. enterica serovar I 4,[5],12:i:- (16.7%), S. Enteritidis (16.1%), S. Bareilly (14.6%), S. Typhimurium (9.9%), and S. Infantis (6.9%). The resistance rates to ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole were 32.6%, 12.1%, and 8.4%, respectively. The resistance rates to cefotaxime and ciprofloxacin were 8.1% and 3.0%, respectively, while 5.4% were multidrug-resistant. S. enterica serovar I 4,[5],12:i:- and S. Enteritidis were highly prevalent, and there was an increase in rare serotypes. Multidrug resistance and ciprofloxacin resistance were highly prevalent. Periodic investigations of Salmonella serotypes and antimicrobial resistance are needed.

Keywords: Serotyping, Antimicrobial resistance, Salmonella